Everton winger Ademola Lookman joins Bundesliga side RB Leipzig on loan until the end of the season.
Burnley midfielder Steven Defour is out for two months as the Belgium international must undergo a knee operation.
Arsenal right-back Mathieu Debuchy joins Saint Etienne on a free transfer after his contract is terminated.
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Tottenham Hotspur: Lloris, Trippier, Sanchez, Vertonghen, Davies, Dier, Dembele, Eriksen, Alli, Son, Kane.
Subs: Rose, Lamela, Wanyama, Vorm, Sissoko, Llorente, Walker-Peters.
Manchester United: de Gea, Valencia, Smalling, Jones, Young, Matic, Pogba, Lingard, Sanchez, Lukaku, Martial.
Subs: Rojo, Mata, Rashford, Romero, Ander Herrera, Shaw, Fellaini.
“Lads, it’s Tottenham.” And to be fair to those who still dine out on the old Roy Keane story, Manchester United retain the sign over Spurs at Old Trafford, which was where Sir Alex Ferguson delivered his famously succinct team talk. United have won 12 of the last 14 stagings of that particular fixture.
But the days when United bossed Tottenham on their own turf too are in the past. Between September 2001 and December 2014, United won eight and drew six of their 14 matches at White Hart Lane, an unbeaten run which included a 4-0 thumping and a 5-3 win from three goals down. Since then, though, Spurs have tightened it up and turned the tide, registering an epochal 3-0 victory in April 2016 and following it up with a 2-1 win in the final match at their famous old stadium last May.
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Chelsea: Courtois, Azpilicueta, Cahill, Christensen, Zappacosta, Kante, Bakayoko, Alonso, Pedro, Barkley, Hazard.
Subs: Caballero, Rudiger, Fabregas, Drinkwater, Moses, Ampadu,
Everton: Pickford, Coleman, Keane, Jagielka, Martina, Gueye, Davies, Walcott, Rooney, Sigurdsson, Niasse.
Subs: Schneiderlin, Williams, Bolasie, Tosun, Calvert-Lewin, Robles, Kenny.
Tottenham complete the signing of Paris St-Germain winger Lucas Moura for a fee in the region of £25m.
Match of the Day pundit Danny Murphy says Wigan’s Nick Powell “oozed class” and “looked like the Premier League player” as he starred in League One Wigan’s FA Cup win over Premier League West Ham United.
Our cartoonist looks at the man who will lead Australia at the World Cup and the next chapter of Tim Cahill’s career
- Take a look back through David’s archive of Australian cartoons
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West Ham loan Reece Oxford back to Bundesliga club Borussia Monchengladbach, but no option for a permanent move has been agreed.
Relive Olivier Giroud’s “sensational” ‘scorpion’ goal in Arsenal’s 2-0 win over Crystal Palace back as the Frenchman signs for Chelsea on an 18-month deal for about £18m.